منابع مشابه
Nucleoli come undone
eceptor tyrosine kinases are often regulated by negative feedback loops that limit their signaling duration. But cells then need to get out of that loop so that they can respond once again. One way to balance the scales is a “signaldependent degradation of a negative regulator,” according to Dafna Bar-Sagi. The inducible degradation of the protein hSpry2, a human homologue of the negative regul...
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Mice lacking Muc2 had an increased ratio of proliferating to apoptotic epithelial cells, resulting in altered maturation and increased migration of epithelial cells in the intestine. They were also more likely to develop intestinal, colon, and rectal tumors. The mice are the first good model for studying rectal tumors, which are common in humans. Anticancer lubrication new mouse model for the s...
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SIR — Rose offers a piece of moral advice in his Commentary. To instruct humankind that they should not do something is a serious undertaking: it should be clear what is enjoined and the consequences acknowledged. Rose seems to argue that, by about 1975, it should have been clear to everyone that the question of genetic causes behind the black/white IQ gap was unanswerable. From that date, ther...
متن کاملSubduction Zones
[1] Subduction zones are where sediments, oceanic crust, and mantle lithosphere return to and reequilibrate with Earth’s mantle. Subduction zones are interior expressions of Earth’s 55,000 km of convergent plate margins and are the geodynamic system that builds island arcs. Excess density of the mantle lithosphere in subduction zones provides most of the power needed to move the plates while in...
متن کاملSubduction zone rheology
Rheological flow laws can be obtained from studies using multi-anvil high-pressure systems with synchrotron-based piezometers and strain metrics. The high flux X-ray source provides minute-scale time resolution with accurate measurement of diffraction patterns and direct sample images. Measurements of length changes with an accuracy of one part in 104 are being developed and will provide a new ...
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ژورنال
عنوان ژورنال: Nature
سال: 2017
ISSN: 0028-0836,1476-4687
DOI: 10.1038/543044a